Therapeutic Benefit
Our unique 2-site HDAC6 binding modality delivers improved drug-like features, enabling us to advance towards potentially life-changing treatments for debilitating diseases.
Next-gen targeting for breakthrough medicines
Breaking Barriers
Conventional drug design approaches have been constrained by their ability to effectively target disease driver proteins, resulting in the failure to translate into meaningful drugs for patients.
HDAX Therapeutics novel modality unlocks a never-seen-before binding mechanism to key biological molecules.
Starting with HDAC6, a validated drug target with applications across a range of diseases with insufficient standards of care, we are building a platform to disrupt the inadequacies of current inhibitors. By transcending traditional limitations, our goal is to unlock the full therapeutic potential of these targets.
Precision Platform
Driven by over 7 years of research and a track record for innovation, HDAX has developed a next-gen solution for a wide range of difficult diseases. Our proprietary 2-site binding mechanism delivers a platform of ultrapotent, highly selective small molecules to tackle critical drug-design challenges.
HDAX refined technology demonstrates enhanced pharmacokinetics, pharmacodynamics, and safety profile, enabling the limitless potential of HDAC6 targeting in diverse indications.
Behind the science: We are a dynamic team of ambitious scientists and creative designers operating at the molecular level
HDAX Advantage
Multi-Indication Application
HDAC6 targeting has demonstrated strong therapeutic potential to be truly disease-modifying in conditions driven by microtubule dysfunction, including peripheral neuropathies, cardiometabolic diseases and more.
Target Safety
The validated safety of HDAC6 targeting, in conjunction with our high selectivity, creates an unrivalled strategy to overcome safety challenges of first-gen medicines.
HDAX precision targeting platform has boundless possibilities
Microtubule Dynamics
Axon Transport
Acetylation Homeostasis
Mitochondrial Regulation
Titin Modulation
